What is Naltrexone?

Naltrexone can interact with other medications and cause dangerous side effects. Since the drug is used to treat alcohol and opioid use disorder, other substances must be avoided at all costs to prevent any sudden withdrawal symptoms. Before using naltrexone, inform your physician of any other medications you’re currently on, including over-the-counter drugs and herbal remedies to avoid complications. The following medications can adversely interact with naltrexone:

• Narcotic drugs, such as codeine and hydrocodone

• Diarrhea medications

• Disulfiram

• Cough medication

Naltrexone is not the same medication as Narcan, also named Naloxone. Although these two medications might look and sound similar, they are however fundamentally different.

The action of naltrexone does not undo the effects of opioids; it prevents the euphoric sensation they cause. On the other hand, Narcan alters the adverse effects of potent opioids. According to the National Institute on Drug Abuse (NIDA), Narcan is a medication designed to reverse an opioid overdose quickly. It is an opioid antagonist that binds itself to opioid receptors and reverses and blocks the effects of other opioids.

When someone is experiencing an opioid overdose, they must seek immediate medical attention. Many emergency healthcare providers have Narcan on hand to counteract a possibly fatal overdose.

It is theoretically possible to overdose on naltrexone, if  someone were to take a massive dosage of opioids or consume a lot of alcohol in an  attempt to counteract the effects of naltrexone, this can lead to an overdose.

A missed naltrexone dose should be taken as soon as possible. But if it’s close to the next dose, it is best to avoid the missed dose. However, take the next dose at the usual time.  Do not double the dosage to catch up on the missed dose as it may lead to an overdose.

Naltrexone works by binding to the endorphin receptors in your brain, effectively blocking the euphoric effects typically produced by alcohol or opioid use. When these receptors are occupied, the chemical “reward” associated with drinking or using drugs is eliminated, which gradually helps to diminish intense cravings over time. At Eleanor Health, our medical providers use Naltrexone as a foundation for long-term recovery, allowing you to focus on therapy rather than the physical urge to use. This evidence-based approach is non-addictive and does not cause physical dependence, making it a safe, effective tool for individuals committed to achieving lasting sobriety through our comprehensive outpatient programs.

The primary difference lies in the method of administration and the duration of the medication’s effects. Oral Naltrexone is a daily pill that requires consistent adherence to be effective, while Vivitrol is an extended-release injectable form administered once every four weeks. Eleanor Health offers both options to fit your specific lifestyle and recovery needs. Vivitrol is often preferred by those who want to remove the daily burden of remembering a pill, providing a steady level of medication in the bloodstream. Our clinical team helps you decide which version is best for your unique situation, ensuring your medication-assisted treatment aligns perfectly with your personal recovery goals.

Unlike some other medications used in addiction treatment, Naltrexone is completely non-addictive and is not a controlled substance. It is an opioid antagonist, meaning it blocks receptors rather than activating them, so it does not produce a “high” or any sedative effects. You cannot become physically dependent on Naltrexone, and there are no withdrawal symptoms if you stop taking it. At Eleanor Health, we emphasize that Naltrexone is a tool to support your brain’s healing process. It serves as a protective shield during your outpatient journey, helping you maintain clarity while you participate in our specialized therapy and peer support sessions.

Most individuals tolerate Vivitrol very well, but some may experience mild side effects as their bodies adjust. Common reactions include nausea, headaches, dizziness, or fatigue, which typically subside within the first few days of the injection. Some patients also report minor soreness or redness at the site of the injection. At Eleanor Health, our providers prioritize your comfort and monitor your physical response closely during every visit. If side effects persist, our clinical team is available to adjust your care plan. We believe that managing physical symptoms is essential to your overall well-being, allowing you to remain fully engaged in your recovery.

Absolutely. At Eleanor Health, we believe that medication is most effective when combined with professional mental health support. While Naltrexone manages the physical cravings, our specialized therapy sessions address the underlying emotional and psychological triggers of addiction. Our “whole-person” care model includes individual counseling, group therapy, and peer support to help you build a robust toolkit for long-term health. We don’t just treat the symptoms; we support the person. By integrating Naltrexone with evidence-based behavioral health services, we empower you to navigate life’s challenges without relying on substances, fostering a sustainable and meaningful path toward a healthier, more fulfilling future.

Naltrexone can interact with certain medications, specifically those containing opioids, such as some cough syrups or prescription painkillers. Because Naltrexone blocks opioid receptors, these medications will not work for pain relief while you are on treatment. During your initial consultation at Eleanor Health, our medical team performs a comprehensive review of all your current prescriptions and supplements. We work collaboratively with you to manage any potential interactions safely. It is important to wear a medical alert tag or inform emergency medical personnel that you are taking Naltrexone, ensuring you receive appropriate and safe care in the event of an unexpected medical emergency.

The duration of treatment is highly individualized and depends on your unique recovery progress and personal goals. Some people use Naltrexone for a few months to navigate early recovery, while others remain on it for a year or longer to maintain stability. At Eleanor Health, we don’t believe in a one-size-fits-all timeline. You will work closely with your dedicated care team to regularly evaluate your progress and determine when it feels right to transition. Our goal is to provide the support you need for as long as you need it, ensuring you feel confident and secure in your sobriety.

Naltrexone is not designed to treat the acute physical symptoms of alcohol withdrawal, such as tremors or seizures. In fact, you should ideally be past the acute withdrawal phase before starting the medication. Instead, Naltrexone is used to support long-term maintenance by reducing the desire to drink and preventing a “slip” from becoming a full relapse. Eleanor Health provides a safe outpatient environment where we can help manage post-acute withdrawal symptoms. Our medical providers ensure that your transition to Naltrexone is timed perfectly, helping to stabilize your brain chemistry so you can focus on the deeper work of healing and personal growth.